中文介绍
Published:2015-01-20 Views:7790

【个人简介】


 

【学习及工作经历】

  •  高中   1994,9-1997,7    湖北省黄冈中学

     本科 1997-2001,7      南京大学化学化工学院

     博士    2001,9-2007,7    中国科学院上海有机所

         导师:唐勇院士,戴立信院士        研究方向: 不对称有机合成

    博士后 2007,10-2010,10    美国迈阿密大学化学与生物化学系    导师: H. Wang 教授

      研究方向:结合小分子催化的双功能催化;新型小分子STAT3 抑制剂的设计与合成

      

    2010,12----- 2015, 9    山东大学化学化工学院副教授, 有机化学专业             

    2015, 9-----       山东大学化学与化工学院破格教授

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【主讲课程】

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    本科生: 有机化学(下册);有机化学实验

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    硕士研究生:高等有机化学

【研究领域和兴趣】

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    研究领域: 有机合成方法学研究以及不对称有机合成

    研究内容:

           1. 结合多种催化方式的协同催化

           2. 金属导向的张力小环化合物有机方法学研究

           3. 新型有机小分子催化的拓展

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【代表论著】

  • Copper(I)-Catalyzed Interrupted Click Reaction: Synthesis of Diverse 5-Hetero-Functionalized Triazoles. Weiguo Wang, Xianglong Peng, Fang Wei, Chen-Ho Tung and Zhenghu Xu* Angew. Chem. Int. Ed. 2016, 55, 649-653.

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  • Arylamine catalyzed Enamine Formation: Cooperative Catalysis of Arylamines with Acids. Yongming Deng, Lu Liu, Ryan G. Sarkisian, Kraig Wheeler, Hong Wang,* Zhenghu Xu* Angew.Chem. Int. Ed. 2013, 52, 3663-3667.

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  • Asymmetric inverse-electron-demand Hetero-Diels-Alder reaction of six-membered cyclic ketones: An enamine – metal Lewis acid bifunctional approach. Zhenghu Xu,Lu Liu, Kraig Wheeler, Hong Wang,* Angew. Chem. Int. Ed. 2011, 50, 3484-3488.

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  • Cu/Pd-Catalyzed, Three-Component Click Reaction of Azide, Alkyne, and Aryl Halide: One-Pot Strategy toward Trisubstituted Triazoles. Fang Wei, Haoyu Li, Chuanling Song, Yudao Ma, Ling Zhou, Chen-Ho Tung, Zhenghu Xu*Org. Lett., 2015, 17, 2860–2863.

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  • Strain Promoted Oxidative Annulation ofArynes and Cyclooctynes with Benzamides: Palladium-Catalyzed C-H/N-H Activationfor the Synthesis of N-Heterocycles. Xianglong Peng, Weiguo Wang, Chao Jiang, Di Sun, Zhenghu Xu*, Chen-Ho Tung. Org. Lett. 2014, 16, 5354.

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  • Synthesis of Spiroaminals and Spiroketals with Bimetallic Relay Catalysis. Xianghua Wang, Shuli Dong, Zhili Yao, Lei Feng, Philias, Daka, Hong Wang, Zhenghu Xu* Org. Lett. 2014, 16, 22.

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  • Synthesis of Fused Bicyclic Aminals through Sequential Gold / Lewis Acid Catalysis. Xianghua Wang, Zhili Yao, Shuli Dong, Fang, Wei, Hong Wang, Zhenghu Xu*, Org. Lett. 2013, 15, 2234.

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  • Synthesis of Spiroaminals with Bimetallic Au/Sc Relay Catalysis: TMS as a Traceless Controlling group. Shuo Zhang, Zhenliang Xu, Jiong Jia,* Chen-Ho Tung, Zhenghu Xu* Chem. Commun2014, 50, 12084.

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  • Dimerization of Cyclopropenes to Bifurans with Tandem Metal Relay Catalysis. Chuanling Song, Di Sun, Xianglong Peng, Jing Bai, Rongyi Zhang, Shengzhen Hou, Jianwu Wang, Zhenghu Xu* Chem. Commun. 2013, 49, 9167.

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  • From Cyclopropenes to Tetrasubstituted Furans: Tandem Isomerization/Alkenylation Sequence with Cu/Pd Relay Catalysis. Chuanling Song, Ling Ju, Mingchao Wang, Yuanzhe Zhang, Jianwu Wang,* Zhenghu Xu* Chem. Eur. J. 2013, 19, 3584.

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  • Synthesis of Quinolinones with Palladium-Catalyzed Oxidative Annulation between Acrylamides and Arynes. Weiguo Wang, Xianglong Peng, Xiaoyu, Qin, Xiangyun Zhao, Chen Ma,* Chen-Ho Tung and Zhenghu Xu* J. Org. Chem. 2015, 80, 2835-2841.

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  • Synthesis of Oxazoles by Tandem Cycloisomerization/Allylic Alkylation of Propargyl Amides with Allylic Alcohols: Zn(OTf)2 as π Acid and σ Acid Catalyst. Bin Wang, Ying Chen, Ling Zhou, Jianwu Wang,* Chen-Ho Tung, and Zhenghu Xu*, J. Org. Chem. 2015, 80, 12718-12724.

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  • Asymmetric Michael Addition of Ketones to Alkylidene Malonates and Allylidene Malonates via Enamine-Metal Lewis Acid Bifunctional Catalysis. Lu Liu, Ryan G. Sarkisian, Zhenghu Xu*, Hong Wang,* J. Org. Chem. 2012, 77, 7693.

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  • Successive Cu/Pd transmetalation relay catalysis in stereoselective synthesis of tetraarylethenes. Chuanling Song, Yihua Sun, Jianwu Wang, Hui Chen,* Jiannian Yao, Chen-Ho Tung and Zhenghu Xu* Org. Chem. Front. 2015, 2, 1366.

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Address: School of chemistry, Shandong univerisity, Jinan, China